Point-of-Care Magnetic Resonance

A Wealth of Diagnostic Information

Based on MRI methods
Accuracy. Convenience. Simplicity.

Livivos's Diagnostic Technology

Livivos’s non-invasive scanning modality is inspired by proven clinical MRI liver scanning principles. The LiverScope® uses open-concept permanent magnet arrays and single-sided radio-frequency antennas to inspect a selected volume inside of the patient’s liver. The scanner does not use ionizing radiation and no contrast agent is necessary.

Livivos offers the accuracy of MRI, but without the inconvenience and anxiety of MRI scans. No appointment burden. No need for prior fasting. No loud noises. No narrow tube causing claustrophobia. Fast and simple.

Non-invasive Inspection of the Liver

Magnetic Resonance technologies have been demonstrated to measure biomarkers for accurate liver fat content, iron overload, and fibrosis. Livivos’s premise is that instead of using a costly MRI examination, these capabilities may be provided by compact, open Magnetic Resonance probes. This results in advantages such as patient comfort, low per-test cost, and ease of scheduling.

The LiverScope® accuracy and unprecedented operational simplicity are critical advantages over other liver fat diagnostic modalities. Livivos’s Magnetic Resonance methods are inspired by the accuracy of MRI, but with the accessibility and convenience of Point-of-Care medical devices such as ultrasound scanners.

Magnetic Resonance

Magnetic Resonance is the base technology in clinical MRI and uses safe radio waves to interrogate materials. The signals are generated by the oscillation of the nuclear spins of the atoms in the interrogated volume. The signal response carries highly specific chemical and molecular dynamic information – driven by the composition and mobility of atoms and molecules. The technology is broadly used in chemical analysis. In order to measure liver fat content, Magnetic Resonance and MRI use the response radio wave signals from hydrogen atoms in water and fat molecules.

Open Magnetic Resonance

From the mid 1990’s, open and compact Magnetic Resonance devices have been used to examine materials outside of the magnet array. Open Magnetic Resonance techniques are effective for analyzing large objects with small probes, in contrast to conventional Magnetic Resonance and MRI scanners, where the object or patient is placed inside of a large superconducting magnet. The open Magnetic Resonance concept requires one-faced magnet arrays and single-sided radio-frequency antennas. The static and radio-frequency magnetic fields projected outside of the probe are used to non-invasively generate Magnetic Resonance signals. Livivos has developed the scanner and diagnostic methods to accurately analyze the liver with remarkable operational simplicity, using patented compact Magnetic Resonance probes.

Diagnostic Methods

Liver disease indicators are accurately graded by analyzing the Magnetic Resonance signals at specific selected volumes inside of the human liver. Livivos’s methods are inspired by effective MRI diagnostic capabilities, which are currently used to differentiate isolated steatosis from NASH and stratify hepatic fibrosis. Livivos’s LiverScope® does not require a whole body MRI scanner or image interpretation. The custom open Magnetic Resonance probe and dedicated proprietary protocols inspect an extended volume inside of the liver. The diagnosis is then completed with remarkable accuracy. For example, PDFF results are immediately generated. PDFF is a leading biomarker for steatosis: reduction in PDFF is associated with NAFLD activity score (NAS) reduction.

“The diagnosis of NASH can be difficult, as most patients in early stages of the disease have no symptoms. The identification of patients is currently not possible by a typical physical examination.”

Top Magn Reson Imaging 2017;26:229

Livivos’s non-imaging Magnetic Resonance methods are based on clinical MRI findings, translated to a Point-of-Care medical diagnosis device.

Clinical MRI

a. Accurate

b. Bottleneck for clinical trials

c. Claustrophobia issues, increase anxiety

d. High ownership and operational costs

e. High degree of operator training

f. Slow scheduling

g. Frequent incidental findings


a. Accurate

b. Speeds up clinical trials

c. Open design. Clothes on. No claustrophobia issues

d. Low ownership and operational costs

e. Training is simple and fast

f. Simple and rapid scheduling

g. No incidental findings


LiverScope® is an investigational medical device. It has not been cleared by the FDA at this time.