LiverScope® is the revolutionizing tool to do it, by transforming the way the disease is diagnosed and managed Livivos aims to halt the ominous worldwide growth of liver disease
Welcome to Livivos, Inc.
Livivos is pioneering a remarkably accurate Point-of-Care liver disease diagnosis modality, promising to transform how the disease is detected, graded, and managed. The innovative approach meets the fast-growing demand for accurate, rapid, and affordable diagnosis of NAFLD and NASH. LiverScope® is aiming to significantly streamline drug efficacy trials as well as increase the availability of accurate diagnostics. Livivos has created a technology platform addressing liver disease diagnosis and potentially expanding into additional medical applications.
With extensive Magnetic Resonance and medical device experience and by teaming with hepatologists and clinical diagnostic experts, Livivos’s mission is to make a significant contribution to human health. LiverScope®’s capabilities address several medical needs in pharmaceutical clinical trials, post-market monitoring, patient triage, and health monitoring.
To improve human health by halting the worldwide growth of liver disease.
To make liver disease diagnosis broadly available by providing accurate, rapid, and accessible Point-of-Care testing.
The Path to LiverScope®
Compact Open Magnetic ResonanceNMR MOUSE
Portable Magnetic Resonance probes for industrial applications are developed in Germany.
Volume Selective Open Magnetic ResonanceSINGLE SIDED MAGNETIC RESONANCE ADVANCES
Use of the open Magnetic Resonance concept to select sensitive volumes outside of the magnet and antenna. Work led by teams in the US and Germany.
Concept DevelopmentLIVER DIAGNOSIS CONCEPT
Open Magnetic Resonance method for human tissue: skin inspection and liver diagnostic concept. Collaborations between Dr. Pablo Prado and MGH-Boston.
LiverScope®, first fully functional scanner is validated using MRI liver fat standards -Calimetrix. (LiverScope® has not been cleared by the FDA.)
Clinical StudiesIN-VIVO LIVER EXAMINATION
UC San Diego Institutional Review Board approval for in-vivo clinical study comparing LiverScope® and MRI liver fat measurements.
Clinical PerformanceUNPRECEDENTED CORRELATION TO MRI
Completion of UC San Diego study demonstrating LiverScope®‘s market-leading performance for Point-of Care liver fat diagnosis.
The people driving Livivos’s revolutionary diagnostics
Pablo J Prado, PhD – CEO, CTO
Dr. Prado is a tech lead with focus on medical device and checkpoint security industries. He was the product introduction lead for 6 products currently in the market – from concept to commercialization. He is the Founder & CEO of ORS and One Resonance, the President of Turbospec, and has been VP of Engineering at Quasar Federal Systems, CTO at Progression Inc., VP of Development at T2 Biosystems (trading TTOO), and Senior Manager and Product Introduction Lead at GE and Quantum Magnetics. He has a PhD in Physics and is a reviewer for the Journal of Magnetic Resonance, Journal of Applied Magnetic Resonance, IEEE Journal of Solid-state Circuits, and also for NIH and DOE SBIR Programs. Dr. Prado is the author of 10 patents, 2 book chapters, and more than 40 scientific articles. See LinkedIn Profile.
Robert Lown – Systems Engineering Lead
Mr. Lown is a world expert in the design and fabrication of compact permanent magnets for Magnetic Resonance and MRI devices. He has over 30 years of experience with 3D solid modeling, thermal analysis, structural design, manufacturing methods, and trouble-shooting of complex electromechanical systems. Mr. Lown has an M.S. in Mechanical Engineering. He has been the engineering lead for clinical MRI product development and several custom state of the art magnetic and mechanical assemblies for institutions such as JPL, Lawrence Berkeley National Laboratory, Los Alamos National Laboratory, Lawrence Livermore National Laboratory, and CERN. He was the Lead Engineer at ORS, Aster Enterprises, Dec-E-Tech, and Field Effects (Intermagnetics General Corp).
Scientific, Medical, and Regulatory Advisors
Claude Sirlin, MD – Head of Liver Imaging Research Group, UCSD
Claude B. Sirlin, MD, is an Associate Professor of Radiology at the University of California, San Diego (UCSD). He received his BA in Biology from Harvard University and his MD from UC San Francisco. He completed residency training in Diagnostic Radiology at UCSD and fellowship training in cross-sectional body imaging (MR, CT, US) at Stanford University. He is Chief of Body MRI, Head of the Liver Imaging Research Group, and Head of Clinical Research, Division of Body Imaging at UCSD – focused on MRI of liver cancer and diffuse liver disease. He has published more than 30 papers, 5 book chapters, 65 scientific abstracts, and 50 educational exhibits, and he reviews for 5 scientific journals. In 2004, Dr. Sirlin formed the UCSD Liver Imaging Group to develop new techniques for liver imaging. The Group actively collaborates with hepatologists, liver surgeons, and pathologists. Dr. Sirlin’s specific areas of interest are liver cancer and diffuse liver disease (fibrosis, fat, and inflammation).
Ariel Feldstein, MD – Chief Gastroenterology and Hepatology, Rady Children’s Hospital
Dr. Feldstein is Chief of the Gastroenterology, Hepatology & Nutrition Division at Rady Children’s Hospital-San Diego and a Professor of Pediatrics at UC San Diego School of Medicine. After graduating from the Univ. of Buenos Aires and completing a postdoctoral program in physiology at the Mayo Clinic, Dr. Feldstein went on to become the Director of Research for the Pediatric Institute at the Cleveland Clinic before moving to San Diego in 2011. Dr. Feldstein has published over 170 peer-reviewed publications, including articles in Nature, Journal of Clinical Investigation, Gastroenterology, Hepatology, Gut, Journal of Hepatology, Journal of Biological Chemistry, and Journal of Immunology. His research laboratory has provided key evidence regarding the role of cell death, innate immune activation, and inflammatory responses during chronic liver injury and carcinogenesis. He is an innovator and an entrepreneur, being the founder of two Biotech Companies, Torrey Pines Metabolic Health Labs and Jecure Therapeutics (acquired by Genentech/Roche in 2018).
Dean Irwin – Quality and Regulatory Lead
Mr. Irwin is an executive and scientific lead with over 30 years of experience in medical device design, development, and certification. He is an expert in the startup environment and has taken four companies from three employees or less to revenue generating or publicly traded viable entities. He has extensive experience across several technical disciplines, has run clinical trials, and has taken multiple products from concept to regulatory clearance from FDA, SFDA, CFDA, KFDA and CE mark. He has published in scientific journals and holds nineteen issued U.S. patents.
Corporate & Intellectual Property Advisors
Adam Shipley – Corporate Law Attorney
Mr. Shipley is a partner in Sheppard Mullin’s Corporate Practice Group. He advises buyers and sellers in acquisition of company, growth capital, and cross border transactions. He is a practical minded lawyer, who focuses in every matter on solving problems and getting deals done efficiently and in a manner that best promotes his client’s commercial objectives. Mr. Shipley has deep experience in the industrial, healthcare, life sciences, and energy sectors. He also has extensive experience in transactions involving cross border matters. He has been honored as a San Diego Rising Star, Super Lawyers, 2016-2019.
Jesse A. Salen – Intellectual Property Attorney
Mr. Salen is an associate in the Intellectual Property Practice Group at Sheppard Mullin. He focuses his practice on trademark and patent prosecution, in addition to intellectual property licensing in the areas of healthcare information technology, software, medical devices, optics, nanotechnology, computer devices, and data storage. Mr. Salen has 16 years of business and technology experience, in both the healthcare and data storage industries. He was the Chief Technology Officer at ONRAD, Inc., a product manager at GE Healthcare, a manager of the customer care program at Hitachi Data Systems, a systems engineer at Memorial Sloan-Kettering Cancer Center, and a research and development engineer in the field of optics and nanotechnology at Micrion Corporation. He has published multiple peer-reviewed articles in the optics and nanotechnology fields, as well as numerous healthcare business journal articles.
With extensive Magnetic Resonance and medical device experience and by teaming with hepatologists and clinical diagnostic experts, Livivos’s mission is to make a significant contribution to human health. LiverScope® addresses critical medical needs in pharmaceutical clinical trials, post-market monitoring, patient triage, and preventive medicine.